CDS

Accession Number TCMCG035C30862
gbkey CDS
Protein Id XP_021631709.1
Location join(12105646..12105930,12118657..12118835,12118943..12119015,12119294..12119416,12119514..12119635,12119725..12119797,12119896..12120012,12120489..12120572,12122894..12123073,12123200..12123328,12141957..12142046,12142616..12142720,12147458..12147492,12148661..12148790,12149645..12149697,12150025..12150124,12154113..12154151,12154658..12154736,12157138..12157209,12161462..12161533,12169345..12169509,12170569..12170689,12170916..12171138)
Gene LOC110629111
GeneID 110629111
Organism Manihot esculenta

Protein

Length 882aa
Molecule type protein
Topology linear
Data_file_division PLN
dblink BioProject:PRJNA394209
db_source XM_021776017.1
Definition DNA topoisomerase 3-alpha isoform X2 [Manihot esculenta]

EGGNOG-MAPPER Annotation

COG_category L
Description Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand
KEGG_TC -
KEGG_Module M00414        [VIEW IN KEGG]
KEGG_Reaction -
KEGG_rclass -
BRITE ko00000        [VIEW IN KEGG]
ko00001        [VIEW IN KEGG]
ko00002        [VIEW IN KEGG]
ko01000        [VIEW IN KEGG]
ko03032        [VIEW IN KEGG]
ko03400        [VIEW IN KEGG]
KEGG_ko ko:K03165        [VIEW IN KEGG]
EC 5.99.1.2        [VIEW IN KEGG]        [VIEW IN INGREDIENT]
KEGG_Pathway ko03440        [VIEW IN KEGG]
ko03460        [VIEW IN KEGG]
map03440        [VIEW IN KEGG]
map03460        [VIEW IN KEGG]
GOs GO:0000003        [VIEW IN EMBL-EBI]
GO:0003674        [VIEW IN EMBL-EBI]
GO:0003676        [VIEW IN EMBL-EBI]
GO:0003677        [VIEW IN EMBL-EBI]
GO:0003824        [VIEW IN EMBL-EBI]
GO:0003916        [VIEW IN EMBL-EBI]
GO:0003917        [VIEW IN EMBL-EBI]
GO:0005488        [VIEW IN EMBL-EBI]
GO:0005575        [VIEW IN EMBL-EBI]
GO:0005622        [VIEW IN EMBL-EBI]
GO:0005623        [VIEW IN EMBL-EBI]
GO:0005634        [VIEW IN EMBL-EBI]
GO:0005654        [VIEW IN EMBL-EBI]
GO:0006139        [VIEW IN EMBL-EBI]
GO:0006259        [VIEW IN EMBL-EBI]
GO:0006260        [VIEW IN EMBL-EBI]
GO:0006265        [VIEW IN EMBL-EBI]
GO:0006725        [VIEW IN EMBL-EBI]
GO:0006807        [VIEW IN EMBL-EBI]
GO:0006996        [VIEW IN EMBL-EBI]
GO:0007049        [VIEW IN EMBL-EBI]
GO:0008150        [VIEW IN EMBL-EBI]
GO:0008152        [VIEW IN EMBL-EBI]
GO:0009058        [VIEW IN EMBL-EBI]
GO:0009059        [VIEW IN EMBL-EBI]
GO:0009987        [VIEW IN EMBL-EBI]
GO:0016043        [VIEW IN EMBL-EBI]
GO:0016604        [VIEW IN EMBL-EBI]
GO:0016605        [VIEW IN EMBL-EBI]
GO:0016853        [VIEW IN EMBL-EBI]
GO:0022414        [VIEW IN EMBL-EBI]
GO:0031974        [VIEW IN EMBL-EBI]
GO:0031981        [VIEW IN EMBL-EBI]
GO:0034641        [VIEW IN EMBL-EBI]
GO:0034645        [VIEW IN EMBL-EBI]
GO:0043170        [VIEW IN EMBL-EBI]
GO:0043226        [VIEW IN EMBL-EBI]
GO:0043227        [VIEW IN EMBL-EBI]
GO:0043229        [VIEW IN EMBL-EBI]
GO:0043231        [VIEW IN EMBL-EBI]
GO:0043233        [VIEW IN EMBL-EBI]
GO:0044237        [VIEW IN EMBL-EBI]
GO:0044238        [VIEW IN EMBL-EBI]
GO:0044249        [VIEW IN EMBL-EBI]
GO:0044260        [VIEW IN EMBL-EBI]
GO:0044422        [VIEW IN EMBL-EBI]
GO:0044424        [VIEW IN EMBL-EBI]
GO:0044428        [VIEW IN EMBL-EBI]
GO:0044446        [VIEW IN EMBL-EBI]
GO:0044451        [VIEW IN EMBL-EBI]
GO:0044464        [VIEW IN EMBL-EBI]
GO:0046483        [VIEW IN EMBL-EBI]
GO:0051276        [VIEW IN EMBL-EBI]
GO:0051321        [VIEW IN EMBL-EBI]
GO:0070013        [VIEW IN EMBL-EBI]
GO:0071103        [VIEW IN EMBL-EBI]
GO:0071704        [VIEW IN EMBL-EBI]
GO:0071840        [VIEW IN EMBL-EBI]
GO:0090304        [VIEW IN EMBL-EBI]
GO:0097159        [VIEW IN EMBL-EBI]
GO:0140097        [VIEW IN EMBL-EBI]
GO:1901360        [VIEW IN EMBL-EBI]
GO:1901363        [VIEW IN EMBL-EBI]
GO:1901576        [VIEW IN EMBL-EBI]

Sequence

CDS:  
ATGATCAACGTCTTGAACGTCGCTGAGAAGCCGTCTGTGGCGAAATCGGTGGCCACCATACTCTCAAGGAACCAACAGCATGGGATGAGAGTTAGGGACGGGCGGTCCCGCTACAACAAGATCTTCGAGTTCAATTACGTGATCAATGGGCAGCCATGCCATATGCTAATGACTTCCGTCACTGGTCATCTTATGGAGCTCGATTTCGAAGATCGCTTTCGCAAATGGCATTCTTGTGATCCCGCTGATCTCTACCATGCCCCCGTCCGGAAATACGTCCCTGAGGACAAGATAGATATCAAAAGGACACTGGAGGAGGAAGCAAGAAGGTGCCAGTGGCTTATTCTATGGCTTGATTGTGATAGAGAGGGAGAAAACATTGCATTTGAAGTGATGGATGTATGTGGAGCAGCAAATCACAACCTTACTATATGGAGGGCTCGCTTTTCTGCATTAATTGACAGGGAAATCCATGAGGCAGCCCAAAATCTTATTTCTCCTAATCAGTGTTTTTCTGATGCTGTGGATGCTAGGCAAGAAATTGATCTCCGCATTGGTGCTTCTTTCACCAGGTTTCAGACCATGTTGTTGAGAGATAAGTTTGTTATTGATTCTGCTCAAGATGACAGAAATCTTGTTCTGAGTTATGGGCCTTGTCAGTTCCCTACACTTGGCTTTATTGTTGAACGTTACTGGGAGATACAATCACATGAGCCTGAAGAGTTTTGGACTATTAATTGTTCTCACAAATCAGATGAAGGCATTGCAAACTTTAGTTGGATGCGTGGACATCTTTTCGATTACACTTCTGCTGTTATACTTTATGAAATGTGTGTTCAGGAACCAACTGCGACTGTAATGAAGGTTCATCAGCAGGAGAAACGGAAGTACCCTCCACATCCTTTGAGTACAATTGAGCTTGAAAAACGTGCCTCAAGATATTTCCGGATGAGTTCTGAACTCACCATGAAAGTGGCAGAAGATCTATACCAAGCTGGTTTCATTAGTTATCCTCGTACAGAAACGGATGGCTTCTCTAGCAGGACTGATTTACATACAATTGTGCGAGAACAACAGGAACATCCTGTATGGGGTTCATATGCTCAACGACTGTTAGATCCTGGAACAGAATTATGGAGAAATCCGGGCAGTGGTGGACATGATGACAAAGCCCATCCTCCCATTCATCCAACAAAGTTTTCTGCTGGTGAAAGTGCATGGAGTCTAGATCATCATAGAGTATATGAGTTAGTTGTTCGCCATTTTCTGGCATGTGTTTCACAACCAGCTATTGGGGCTGAAACTATTGTTGAAATTGATATTGCTGGTGAACAGTTTTCTGCATCAGGGAGGGTGATATTAGTTTTTCTCCCGACAACCTTGGCTCTTGATTCAGGAGTCACTAGACCACCACCTCTTCTAAGTGAAGCAGATTTACTTAGCTGTATGGACAAGGCTGGTATTGGTACGGATGCGACGATGCATGATCACATAAAGAAGCTGCTTGATCGATTCTATGCAACAAAGGATACGAATACTCGTTTCTCACCAACTAATCTTGGTGAGGCTCTGGTTATGGGATATGATGACATGGGATATGAACTTTGGAAACCAAATCTTAGATCAATGATGGAGTTTGACATGAAACAAGTTAGCATGGGCTGTAAACGTAAAGCTGAAGTATTGGATACTTGCTTGCAACAGATGAAAGCTTGCTTCTTAGATGCAAGGGTAAATAAAGTGAAACTCCTAGAAGCCATGGCTATATTCTTTGGGAGATCAGATAGATATGGAGGAAATGACCATCATGTAGCTGCAGAAATTGTTCGACCATGTGGACTTTGTCAGGAATCAAATATGGTGCTAAGACGAAGCCGGGATGGCAATTTCATGGTTGGATGCTTGGGGTTTCCACAGTGTAGGAATGCTATATGGCTTCCTGGACCAGTACTTGAAGCCACTGTAAGCACCAACATTTGCAACTGCTGCACGCCAGGTCCTGTTTACTTGATTCAATTCAAGTTTCGGCAGCTTGAAATACCACCAGGCTTCAATGTCAACCATTTAGGTTGCATCGGTGGCTGTGATGAGACTTTGAGACAGTTGATAGAGATATGTGGAACTGGTTCTCGTGTACAAGCCAGAGGTCATGCACCTAATCCAACACCTGGCAACCTCCAACAAAATAACATTAGGCGTGGTACTTGCATTCACTGTCAGCAATTGGGACATGCTTCAAGCAATTGCCCTTCACAATTTTCAGCTTCTCGACATGCTCAGTTCAATGGAATGAGACCACAAACTGGGGAATCTTCAGTTTCATGTGGGACATGTGGAGCACAATGTGTTTTGCGTACGGCTAATACAGCAAATAACAGGGGAAGAAAGTTCTACTCATGTCCATCTCAAGGATGCAACTTTTTTGTATGGGAGGACAACTCGAATAATGGCACCTATGGAACAAATGCAAATGTCAGTAACTCGGCATCTAATCCTAGCTGGAGCAGGAGGGGTGGCCGTGGCAGGGGTACACAGGGTGGTGGGACTTTTGTTTCTGCCACTGGTGATCCTGTATCTGGCAGGTGTTATATGTGTGGTGATCCATCACACTTTGCAAATACCTGTCCAAATCGTGGTTCGCGATGGTGA
Protein:  
MINVLNVAEKPSVAKSVATILSRNQQHGMRVRDGRSRYNKIFEFNYVINGQPCHMLMTSVTGHLMELDFEDRFRKWHSCDPADLYHAPVRKYVPEDKIDIKRTLEEEARRCQWLILWLDCDREGENIAFEVMDVCGAANHNLTIWRARFSALIDREIHEAAQNLISPNQCFSDAVDARQEIDLRIGASFTRFQTMLLRDKFVIDSAQDDRNLVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTINCSHKSDEGIANFSWMRGHLFDYTSAVILYEMCVQEPTATVMKVHQQEKRKYPPHPLSTIELEKRASRYFRMSSELTMKVAEDLYQAGFISYPRTETDGFSSRTDLHTIVREQQEHPVWGSYAQRLLDPGTELWRNPGSGGHDDKAHPPIHPTKFSAGESAWSLDHHRVYELVVRHFLACVSQPAIGAETIVEIDIAGEQFSASGRVILVFLPTTLALDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDTNTRFSPTNLGEALVMGYDDMGYELWKPNLRSMMEFDMKQVSMGCKRKAEVLDTCLQQMKACFLDARVNKVKLLEAMAIFFGRSDRYGGNDHHVAAEIVRPCGLCQESNMVLRRSRDGNFMVGCLGFPQCRNAIWLPGPVLEATVSTNICNCCTPGPVYLIQFKFRQLEIPPGFNVNHLGCIGGCDETLRQLIEICGTGSRVQARGHAPNPTPGNLQQNNIRRGTCIHCQQLGHASSNCPSQFSASRHAQFNGMRPQTGESSVSCGTCGAQCVLRTANTANNRGRKFYSCPSQGCNFFVWEDNSNNGTYGTNANVSNSASNPSWSRRGGRGRGTQGGGTFVSATGDPVSGRCYMCGDPSHFANTCPNRGSRW